1. my.clevelandclinic.org

    Oct 18, 2023A demyelinating disease affects your myelin sheath. This is a protective cover that surrounds nerve cells. Damage to your myelin can happen if your immune system mistakes healthy nerve cells for harmful ones. The most common demyelinating disease is multiple sclerosis. Treatment varies based on what type of demyelinating disease affects you.
  2. verywellhealth.com

    Apr 14, 2024Vitamin deficiencies: Vitamins serve many functions in the body, including helping myelin production. Vitamin B12 deficiency can contribute to demyelinating disease of the spine as well as peripheral neuropathy. Similar to B12 deficiency, copper deficiency can affect the spinal cord and peripheral nerves. Low copper can occur in those with a ...
  3. mayoclinic.org

    Apr 27, 2024When the myelin sheath is damaged, nerve impulses slow or even stop. This can cause neurological symptoms such as trouble walking or seeing, or changes in bowl and bladder function. Multiple sclerosis. Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system. In this disease, the immune system attacks the ...
  4. sciencedirect.com

    The recently described 'transient myelin deficiency ' caused by TMEM63A pathogenic variants (similar to PMD with no detectable myelin and normalisation on later MRIs after 4 years of age) further illustrate the complexity of the terminologies [44]. The confusion exists because semantic updates do not catch up with the expanding knowledge on ...
  5. en.wikipedia.org

    A demyelinating disease refers to any disease affecting the nervous system where the myelin sheath surrounding neurons is damaged. [1] This damage disrupts the transmission of signals through the affected nerves, resulting in a decrease in their conduction ability. Consequently, this reduction in conduction can lead to deficiencies in sensation, movement, cognition, or other functions ...
  6. sciencedirect.com

    Histopathological analysis performed in one case confirmed the myelin deficiency which seems to be related to both hypomyelination and mild myelin degeneration. The density of white matter oligodendrocytes appeared reduced. Only a few remaining pyknotic neurons with gliosis were observed in the putamen and the caudate nucleus whereas the ...
  7. msdmanuals.com

    Myelin sheaths cover many nerve fibers in the central and peripheral nervous system; they accelerate axonal transmission of neural impulses. Disorders that affect myelin interrupt nerve transmission; symptoms may reflect deficits in any part of the nervous system. ... Vitamin B12 deficiency. Direct viral invasion of CNS. Progressive multifocal ...

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